Effect of Bone Protein addition to the system: Calcium Titanate

Authors

  • Fadhil K. Farhan AL-Karkh University of Science, College of Science, Baghdad, Iraq
  • Mazin Mohammed Mawat AL-Karkh University of Science, College of Science, Baghdad, Iraq
  • Jafer Fahdel Odah AL-Karkh University of Science, College of Science, Baghdad, Iraq

DOI:

https://doi.org/10.15330/pcss.25.4.880-884

Keywords:

Bone calcium titanate, manufacturing powders, nano-scale titanium dioxide, synthesized bone protein

Abstract

A ceramic compound was prepared by mixing calcium carbonate in a mole ratio to nanoscale titanium dioxide powder using the method of manufacturing powders, in addition to mixing and grinding for long hours up to 72 hours in the presence of non-ionic water. After which the powder was extracted and then it was dried at a temperature of 100 oC for 4 hours, and then it was treated at 800 oC in a convection oven at 10 oC of heat for every 2 minutes. An X-ray diffraction test of the ceramic powder was performed before adding the synthesized bone protein that was prepared from cow bones. Scanning electron microscopy and energy dispersion spectrometry were also performed before and after adding the BMP. The results of the examination showed a big difference in the properties of the compound in terms of the atomic structure, as new compounds of bone components were introduced into the atomic structure, and the results were interpreted through the practical intensity of examining the body fluid-like solution (SBF).

References

D.H. Kempen, L.B. Creemary, Growth factor interactions in bone regeneration tissue, Eng. Bart. B., 16(6), 551 (2010); https://doi.org/10.1089/ten.teb.2010.0176.

Haiping Lu, Yinghong Zhou, Yaping Ma, Lan Xiao, Wenjun Ji, Yi Zhang and Xin Wang, Current Application of Beta-Tricalcium Phosphate in Bone Repair and Its Mechanism to Regulate Osteogenesis, Front. Mater., 8, 698915 (2021); https://doi.org/10.3389/fmats.2021.698915.

C. Romagnoli, F. D'Asta and M. L Brandi, Drug delivery using composite scaffolds in the context of bone tissue engineering, Clin. Cases. Miner. Bone Metab. 10(3), 155(2013).

L. Dupoirieux, D. Pourquier, M. Neves and L. Teot, Resorption kinetics of eggshell: an in vivo study, J. Craniofac. Surg. 12(1), 53 (2001); https://doi.org/10.1097/00001665-200101000-00009.

E. Durmus, I. Celik, M.F. Aydin, G. Yildirim and E. Sur, Evaluation of the biocompatibility and osteoproductive activity of ostrich eggshell powder in experimentally induced calvarial defects in rabbits, J. Biomed. Mater Res. B Appl. Biomater. 86(1). 82 (2008); https://doi.org/10.1002/jbm.b.30990.

K Gavenis, U. Schneider, J. Groll, B.Schmidt-Rohlfing, BMP-7-loaded PGLA microspheres as a new delivery system for the cultivation of human chondrocytes in a collagen type I gel: the common nude mouse model, Int J Artif Organs 33(1), 45 (2010); https://doi.org/10.1177/039139881003300107.

Diana-Elena Radulescu, Ionela Andreea Neacsu, Alexandru-Mihai Grumezescu and Ecaterina Andronescu, Review Novel Trends into the Development of Natural Hydroxyapatite-Based Polymeric Composites for Bone Tissue Engineering, Polymers, 14, 899 (2022); https://doi.org/10.3390/polym14050899.

HK Kim, JH Kim, DS Park, KS Park, SS Kang, JS. Lee et al. Osteogenesis induced by a bone forming peptide from the prodomain region of BMP-7, Biomaterials, 33(29), 7057 (2012); https://doi.org/10.1016/j.biomaterials.2012.06.036.

A. Uraz, SE. Gultekin, B. Senguven, B. Karaduman, IP. Sofuoglu, S. Pehlivan et al. Histologic and histomorphometric assessment of eggshell-derived bone graft substitutes on bone healing in rats. J Clin Exp Dent;5(1), e23 (2013); https://doi.org/10.4317/jced.50968.

M. Dhonde, K. Sahu, V.V.S. Murty, S.S. Nemala, P. Bhargava and S. Mallick, Enhanced photovoltaic performance of a dye sensitized solar cell with Cu/N Co-doped TiO2 nanoparticles, J. of Mat. Sci.: Mat. in Electronics, 29(8), 6274 (2018); https://doi.org/10.1007/s10854-018-8605-3.

J.O. Carneiro, S. Azevedo, F. Fernandes, E. Freitas, M. Pereira, C.J. Tavares, S. Lanceros and V. Teixeira, Synthesis of iron-doped TiO2 nanoparticles by ball-milling process: the influence of process parameters on the structural, optical, magnetic, and photocatalytic properties, J. Mater. Sci., 49 (21), 7476 (2014); https://doi.org/10.1007/s10853-014-8453-3.

Asma Manzari-Tavakoli1, Amirhesam Babajani, Mohammad Hadi Farjoo, Mostafa Hajinasrollah, Soheyl Bahrami and Hassan Niknejad, The Cross-Talks Among Bone Morphogenetic Protein (BMP) Signaling and Other Prominent Pathways Involved in Neural Differentiation, Front. Mol. Neurosci., 15(15), 827275 (2022); https://doi.org/10.3389/fnmol.2022.827275.2022.

É. R. Oliveira, L. Nie, D. Podstawczyk, A. Allahbakhsh, J. Ratnayake, D. Lima Brasiland Amin Shavandi, Advances in Growth Factor Delivery for Bone Tissue Engineering, Int J Mol Sci. 22(2), 903 (2021); https://doi.org/10.3390/ijms22020903.

Tao Li, M. S., Liang Fang, Fengang Zheng, Xinglong Wu., Effect of Ca deficiencies on the photoluminescence of CaTiO3:Pr3+. Journal of Alloys and Compounds, 474(1), 330 (2009); https://doi.org/10.1016/j.jallcom.2008.06.076.

Hidekazu Tanaka, H.T., Ken’ichi Ota, and Tomoji Kawai. Molecular-dynamics prediction of structural anomalies in ferroelectric and dielectric BaTiO3-SrTiO3-CaTiO3 solid solutions, Physical Review B, 53(21), 14112 (1996); https://doi.org/10.1103/PhysRevB.53.14112.

J.P. Wiff , V.M. Fuenzalida, J.L. Arias, M.S. Fernandez, Hydrothermal–electrochemical CaTiO3 coatings as precursor of a biomimetic calcium phosphate layer, Materials Letters 61, 2739 (2007); https://doi.org/10.1016/j.matlet.2006.06.092.

Downloads

Published

2024-12-13

How to Cite

Farhan, F. K., Mawat, M. M., & Odah, J. F. (2024). Effect of Bone Protein addition to the system: Calcium Titanate . Physics and Chemistry of Solid State, 25(4), 880–884. https://doi.org/10.15330/pcss.25.4.880-884

Issue

Section

Scientific articles (Physics)